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What is Hyalgan?

Hyalgan 20mg is a hyaluronic acid-based injectable product designed to relieve pain associated with osteoarthritis (OA) of the knee in patients who have failed to respond to nonpharmacologic treatment and basic analgesics such as acetaminophen.
Hyaluronic acid is a major component of synovial fluid, a viscous liquid that protects joints and helps to avoid inflammation. Osteoarthritis is caused by the lack of hyaluronic acid in the synovial fluid, which results in pain and stiffness in the joints, worsening with age. Sodium hyaluronate in Hyalgan substitutes the natural fluid and functions as a lubricant and a shock absorber when injected into the affected joint. Hyalgan aids in the correct functioning of the joints, therefore reducing discomfort and helping patients regain their quality of life.

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What are the contraindications to the use of the product?

Hyalgan is not recommended for use in pregnant and breastfeeding women, as well as children under the age of 18.

Because Hyalgan contains animal-derived hyaluronic acid, patients with a known hypersensitivity to poultry protein must avoid using this product.

It is advisable to use the product cautiously in patients with weak liver function or poor blood coagulation. There should also be no skin infections or signs of inflammation in or around the treatment area.

How to use Hyalgan?

Hyalgan is injected directly into the articular cartilage. The course of treatment consists of 3–5 injections, which are given at weekly intervals. The number of procedures required varies depending on the patient’s physical characteristics, the body’s response to the medication, and other relevant factors. Three injections given at weekly intervals may be enough for certain patients. This has been reported in published research where individuals were monitored for 60 days after receiving three injections.

Hyalgan works for four to six months after being administered. The product’s effects may be enhanced by adding physical therapy.

Side effects

Any potential adverse effects should be discussed with your doctor before the therapy starts.

Local reactions to the treatment may include pain, edema, redness, rash, or itching at the injection site. Temporary dizziness and nausea are possible adverse effects. Some patients experience temporary joint stiffness, synovitis, and ecchymosis.

If you notice any symptoms of an allergic reaction to the treatment, please seek immediate medical attention.

Contents of the package

Hyalgan comes in 2ml single-use pre-filled syringes as a sterile, non-pyrogenic solution.